FIG. 6.

Degradation of extracellular applied H₂O₂ by single MCs. CA experiments were conducted at 650 mV in PBS-I buffer using a 10 μm Pt-UME versus Ag/AgCl. The UME was placed 5–8 μm above the MC. (A) An MC was challenged first with the solvent DMSO (0.2%) and 30 min later with H₂O₂ (20 μM). (B) A different MC was treated in the same way as described in (A), and then a 2D scan was started 5 min after H₂O₂ application [C, green square corresponds to the time point in (A)]. The dashed white circle marks the position of the MC (B) during scanning procedure. Scan settings were the same as in Figure 3. (D) A cell-free control CA experiment over more than 4 h in the absence or presence of H₂O₂ (n = 3).