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. Author manuscript; available in PMC: 2018 Jul 23.
Published in final edited form as: Leuk Lymphoma. 2017 May 16;58(12):2916–2925. doi: 10.1080/10428194.2017.1319052

Figure 1. P-gp overexpression positively correlates with HIF-1α expression in MM plasma cells.

Figure 1

(A) Gene expression analysis of P-gp (ENSG00000085563) and HIF-1α (ENSG00000100644) in MM patients stratified into HIF-1αlow (n=108), HIF-1αint (n=430) and HIF-1αhigh (n=126) based on the CoMMpass trial dataset. (B) Gene expression analysis of P-gp (ID probe 209993_at) and HIF-1α (ID probe 200989_at) in MM patients stratified into HIF-1αlow (n=98), HIF-1αint (n=348) and HIF-1αhigh (n=113) based on published datasets from the Gene Expression Omnibus by Zhan et al. Results are shown as mean ± standard deviation (s.d.); the statistical significance was assessed by one-way ANOVA (*** p<0.0001).