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(A) Representative pictures of gross buccal tumors arising from oncogene cotransfection in C57BL/6NCr mice. Plasmids contained HPV16-E6/E7, luciferase, NRasG12V, and SB100. (B) Representative histology sections with H&E stain and special IHC staining with Ki-67 and NRas. (C) Representative images for RNAscope targeting HPV16 RNA and IHC staining with HPV-associated biomarker p16. Three independent experiments were performed.
