Table 3. Comparison of cross-reactivity of insulin analogs in various insulin assays.
System | Lumipulse G1200 (Fujirebio Inc., Tokyo, Japan) | Roche E170 (Roche Diagnostics, Mannheim, Germany) | Architect (Abbott Laboratories, IL, USA) | Immulite 2000 (Siemens Healthcare Diagnostics, NY, USA) | Unicel DxI Access (Beckman Coulter, CA, USA) | Advia Centaur (Siemens Healthcare Diagnostics, NY, USA) | Cisbio International (Schering, MA, USA) | IMx (Abbott Park, IL, USA) | Coat-A-Count (Siemens Healthcare Diagnostics, NY, USA) | E-test TOSOH II (Tosoh Co., Tokyo, Japan) |
---|---|---|---|---|---|---|---|---|---|---|
Humulin | + | + | + | + | + | + | + | + | + | + |
Insulin aspart | − | − | + | + | + | + | + | + | + | + |
Insulin lispro | − | − | + | + | + | + | + | + | + | + |
Insulin glulisine | − | − | ± | − | + | − | − | Not available | Not available | Not available |
Insulin detemir | − | − | + | − | + | + | + | Not available | Not available | Not available |
Insulin glargine | ± | ± | + | + | + | + | + | + | + | ± |
Reference | This study, 13 | 10,11,14,24,25,29,33 | 14,25,31,33 | 10,11,14,24,25,33 | 14,24,32,33 | 10,11,14,24,25,33 | 14 | 11,14,36 | 14,24 | 31 |