Table 5. Comparison of the QMAP system and REBA MTB-MDR assay for detection of RIF and INH resistance.
| REBA MTB-MDR | QMAP system | Agreement, % (95% CI) | Kappa* | |
|---|---|---|---|---|
| MT, N | WT, N | |||
| RIF | ||||
| MT | 121 | 0 | 98.5 | 0.968 | 
| WT | 3 | 76 | (0.9548–0.9969) | |
| INH | ||||
| MT | 109 | 0 | 99.5 | 0.990 | 
| WT | 1 | 90 | (0.9694–1.0000) | |
*Values ≥0.75 indicate especially good agreement.
Abbreviations: CI, confidence interval; QMAP, Quantamatrix Multiplexed Assay Platform; REBA, reverse blot hybridization; MTB, Mycobacterium tuberculosis; MT, mutant type; WT, wild type; RIF, rifampicin; INH, isoniazid.