Table 1.
Comparison table of the average composition ratio (%) of 15 biliary bile acids in CCA, BBD and PC patients.
| CCA | BBD (p-value) | PC (p-value) | |||
|---|---|---|---|---|---|
| LCA | 0.04 | 0.02 | (NS) | 0.02 | (NS) |
| UDCA | 0.15 | 1.32 | (NS) | 0.02 | (NS) |
| CDCA | 0.10 | 1.67 | (NS) | 1.00 | (NS) |
| DCA | 0.00 | 0.27 | (NS) | 0.31 | (NS) |
| CA | 0.27 | 2.37 | (NS) | 1.13 | (NS) |
| GLCA | 0.13 | 0.72 | (NS) | 0.32 | (NS) |
| GUDCA | 5.44 | 6.03 | (NS) | 2.66 | (NS) |
| GCDCA | 16.06 | 17.10 | (NS) | 14.22 | (NS) |
| GDCA | 1.37 | 4.97 | (0.0009) | 3.39 | (0.2) |
| GCA | 35.58 | 22.33 | (<0.0001) | 19.95 | (<0.0001) |
| TLCA | 0.01 | 0.10 | (0.006) | 0.06 | (0.3) |
| TUDCA | 1.48 | 2.75 | (NS) | 1.00 | (NS) |
| TCDCA | 7.31 | 12.45 | (0.001) | 13.82 | (0.002) |
| TDCA | 0.48 | 2.74 | (0.004) | 2.14 | (0.1) |
| TCA | 31.56 | 25.15 | (0.04) | 39.96 | (0.04) |
Datasets were analyzed using one-way analysis of variance (ANOVA) to determine if there is a significant difference in the average composition ratio (%) of biliary bile acids in CCA, BBD and PC patients. NS indicates that the ANOVA did not show a significant difference (p < 0.05) among the three patient groups. When ANOVA p < 0.05, p-values are indicated for pairwise comparisons between CCA and BBD patients and between CCA and PC patients (protected Fisher’s least significant difference (LSD) posthoc test).