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. 2018 Jul 23;8:11059. doi: 10.1038/s41598-018-29427-1

Figure 2.

Figure 2

Case examples applying SPoT and qSOFA vital-signs criteria. The SPoT Vital-Signs Criterion was positive when SBP < 100 mmHg and/or HR > SBP; the earliest time that the criterion was met is indicated by shaded boxes in the two case illustrations. The qSOFA Vital-Signs Criterion was positive at the earliest time that at least two of the three constituent conditions were met: (i) Respiratory rate ≥ 22 per min; (ii) GCS < 15; and (iii) SBP ≤ 100 mmHg.7 At any time that there was one documented vital-sign abnormality, we checked earlier in the record to see if there was prior documentation of a second vital-sign abnormality that would make the qSOFA vital-signs criterion positive; the earliest time that the criterion was met is indicated by the later of the connected solid circles in the case illustrations. The Alternative qSOFA Vital-Signs Criterion was also explored, which required at least two of the three constituent qSOFA conditions be met within the same set of documented vital signs; the earliest time that the Alternative qSOFA criterion was met is indicated by dashed circles in right-hand panel, whereas this criterion was never met in the left-hand panel. We determined that this Alternative qSOFA yielded generally reduced sensitivity and increased Time to (+) Screen, and it was therefore omitted from further investigation.