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. 2018 Jul 23;8:11078. doi: 10.1038/s41598-018-29474-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The impact of CTGF/CTGF+ASC treatment on CD146⁺ tendon progenitor/stem cell expression. (a) Changes in relative abundance of CD146 gene MCAM in flexor tendons 14 days after repair and indicated treatments. ^{^}P < 0.05 compared to paired uninjured tendons by paired t-tests. (b) Annotated coronal section of a repaired flexor tendon indicating locations of regions of interest. (c) Representative images and quantifications of CD146 staining at the indicated regions of interest in flexor tendons from three repair groups. The sections are ~250 µm from the volar surface of the tendons. ^*P < 0.05, by Student-Newman-Keuls post-hoc tests.