Table 2.

The results of meta-analysis after removing the studies deviated from HWE.

Ethnicity	Studies	Meta-analysis			Heterogeneity test		Association
		OR	95% IC	P value	I2	P value
the allele model
integrated population	All	0.875	[0.8543; 0.8955]	<0.0001	9.9%	0.2764	significant
integrated population	In HWE	0.875	[0.8524; 0.8960]	<0.0001	11.4%	0.2560	significant
Asian	All	0.927	[0.8777; 0.9786]	0.0034	34.8%	0.0734	significant
Asian	In HWE	0.928	[0.8752; 0.9845]	0.0131	39.4%	0.0706	significant
East Asian	All	0.918	[0.8673; 0.9725]	0.0036	41.8%	0.0501	significant
East Asian	In HWE	0.932	[0.8781; 0.9898]	0.0218	42.8%	0.0573	significant
China	All	0.939	[0.8782; 1.0040]	0.0654	47.1%	0.0355	not significant
China	In HWE	0.962	[0.8959; 1.0332]	0.2884	46.2%	0.0534	not significant
the dominant model
integrated population	All	0.848	[0.8171; 0.8794]	<0.0001	0.0%	0.5996	significant
integrated population	In HWE	0.848	[0.8169; 0.8803]	<0.0001	0.6%	0.4558	significant
Asian	All	0.922	[0.8464; 1.0050]	0.0649	16.0%	0.2917	not significant
Asian	In HWE	0.940	[0.8558; 1.0326]	0.1969	28.1%	0.2037	not significant
East Asian	All	0.934	[0.8545; 1.0205]	0.1304	19.2%	0.2717	not significant
East Asian	In HWE	0.946	[0.8588; 1.0418]	0.2591	36.9%	0.1494	not significant
China	All	0.988	[0.8868; 1.1008]	0.8270	0.0%	0.4601	not significant
China	In HWE	1.026	[0.9072; 1.1612]	0.6794	2.4%	0.4013	not significant
the recessive model
integrated population	All	0.822	[0.7790; 0.8676]	<0.0001	32.6%	0.0387	significant
integrated population	In HWE	0.824	[0.7799; 0.8695]	<0.0001	0.0%	0.5382	significant
Asian	All	0.747	[0.5112; 1.0924]	0.1326	70.5%	0.0002	not significant
Asian	In HWE	0.861	[0.7089; 1.0454]	0.1305	47.7%	0.0631	not significant
East Asian	All	0.675	[0.4441; 1.0254]	0.0654	68.1%	0.0015	not significant
East Asian	In HWE	0.883	[0.7221; 1.0795]	0.2246	51.9%	0.0524	not significant
China	All	0.615	[0.3546; 1.0677]	0.0841	71.8%	0.0008	not significant
China	In HWE	0.892	[0.6767; 1.1750]	0.4154	59.8%	0.0291	not significant