Fig. 1. A 40-year-old male was diagnosed as having cardiac MFH (Patient-1).

a The pedigree of the Patient-1's family. (1) Unknown reason death; (2) esophageal carcinoma; (3) neuroglioma; (4) acute myeloid leukemia. A sibling (54s) of the patient, who only carries the FH (E404D), once accepted the benign sarcoma resection on the back. In this study, FH (E404D) and ACOX2 (R409H) were paternally and maternally derived, respectively. b Imaging modalities for identification and characterization of a primary cardiac tumor in Patient-1. Transthoracic echocardiogram and chest X-ray revealed increased cardio-thoracic ratio due to a 10 × 5.5 cm² tumor in the right ventricle (RV). c The irregular and heterogenous pieces of sarcoma were resected from RV during the surgery