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. 2018 Jul 23;28:28. doi: 10.1038/s41533-018-0095-5

Table 4.

Multivariable analysis of the sub-group of patients with PEF data available describing risk predictors for at least one asthma attack defined by the American Thoracic Society criteria

Reference category Comparison Odds ratio (95% CI) p Value Overall p value
Blood eosinophil count
≤400/µL >400/µL 1.48 (1.15, 1.91) <0.001 0.002
GINA management step
0 1/2 1.04 (0.67, 1.61) 0.867 <0.001
3 1.65 (1.00, 2.73) 0.050
4/5 2.53 (1.43, 4.46) 0.001
GP consults for LRTIs
0 1+ 1.48 (1.02, 2.14) 0.040 0.003
Asthma attack
0 1 3.72 (2.73, 5.06) <0.001 <0.001
2+ 7.81 (5.18, 11.76) <0.001
% predicted PEF
Per 1% increase 0.995 (0.990, 1.000) 0.036 0.036
Age
Per year of age 0.92 (0.87, 0.97) 0.004 0.004

The results are from a multivariable analysis. The following variables were significantly associated with asthma attack in the univariate analyses but were not significant in the multivariate model: hayfever diagnosis ever, eczema diagnosis ever, overall asthma control, daily short-acting β-agonist dosage and average inhaled corticosteroid daily dose.

GINA Global INitiative for Asthma, LRTI Lower respiratory tract infection