Table 2.
Action potential duration at 30, 50, 70 and 90% of repolarization (APD30, APD50, APD70 and APD90 respectively) measured in myotubes derived from patient 1 and patient 2.
| Injectedcurrent (pA) | ||||
|---|---|---|---|---|
| 550 | 750 | 1000 | ||
| APD30 (ms) |
Patient 1 | 2.64 ± 0.4* (n = 20) | 2.75 ± 0.3* (n = 21) | 2.64 ± 0.3* (n = 21) |
| Patient 2 | 3.30 ± 0.3 (n = 21) | 3.19 ± 0.2 (n = 26) | 3.16 ± 0.2 (n = 34) | |
| APD50 (ms) |
Patient 1 | 4.33 ± 0.6 (n = 20) | 4.44 ± 0.5 (n = 21) | 4.29 ± 0.5 (n = 20) |
| Patient 2 | 4.96 ± 0.5 (n = 22) | 4.90 ± 0.4 (n = 27) | 4.82 ± 0.3 (n = 35) | |
| APD70 (ms) |
Patient 1 | 7.57 ± 1.0 (n = 20) | 7.63 ± 1.0 (n = 21) | 6.87 ± 0.8 (n = 21) |
| Patient 2 | 7.72 ± 0.9 (n = 22) | 7.68 ± 0.8 (n = 27) | 7.48 ± 0.6 (n = 35) | |
| APD90 (ms) |
Patient 1 | 26.20 ± 6.4* (n = 20) | 24.00 ± 6.6* (n = 21) | 17.09 ± 2.4* (n = 21) |
| Patient 2 | 15.04 ± 2.3 (n = 22) | 15.15 ± 2.2 (n = 27) | 14.13 ± 1.7 (n = 34) | |
The number of independent experiments were 5 for both the patients. *p < 0,05