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. 2018 Jul 23;8:11096. doi: 10.1038/s41598-018-29420-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Characterization of differentially expressed genes in bovine mammary tissue between heat-stressed (HT) and cooled (CL) dairy cattle across the dry period. Differentially expressed genes (DEGs, nominal p ≤ 0.005, absolute log fold change ≥ 0.5) in the bovine mammary between heat-stressed (n = 6) and cooled (n = 6) dairy cattle consistently up- or downregulated at D7, 14, and 25 relative to dry-off (D0, ~46 d relative to expecting calving). Expression is quantified in HT relative to CL cows. Red indicates upregulation, green indicates downregulation. The y-axis displays the -log₂ fold change of each DEG and the x-axis lists the gene name.