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. 2018 Jul 17;12:456. doi: 10.3389/fnins.2018.00456

Table 1.

Summary of different nano-architecture fabrication techniques.

Nano-architecture technique Compatible materials Resolution time required Cost Serial or batch processing Features References
Electron beam lithography Silicon and conductive materials. Requires electron-sensitive resist (i.e., PMMA) Below 10 nm Slow for scanning focused electron beam High-equipment cost (>$1 million) Serial for focused electron beam; batch processing possible for projection electron beam lithography; device-scale or wafer-scale Often used to create master mold for nano-imprint lithography Tseng et al., 2003; Dong et al., 2005a; Joo et al., 2006; Lee et al., 2007; Dalby et al., 2008; Yang and Leong, 2010; Scholten and Meng, 2016
Nano-imprint lithography Silicon-based materials, metals, polymers 2–100 nm Relatively fast to transfer pattern from mold to resist High cost of master mold, but overall cost is relatively low due to reusability of mold Batch processing; device-scale or wafer-scale Two broad categories: thermal NIL and ultraviolet NIL Chen and Ahmed, 1993; Schulz et al., 2000; Dong et al., 2005b; Guo, 2007; Li et al., 2011; Al-Abaddi et al., 2012; Choi et al., 2013; Eom et al., 2015; Baquedano et al., 2017
Focused ion beam lithography Silicon-based materials, metals, and polymers ∼20 nm Slow rate of milling High-equipment cost (>$1 million) Serial processing on device-scale Direct write; flexible design and materials Watkins et al., 1986; Veerman et al., 1998; Lehrer et al., 2001; Reyntjens and Puers, 2001; Heyderman et al., 2003; Gabay et al., 2005; Kim et al., 2007; Lanyon and Arrigan, 2007; Raffa et al., 2008; Christopherson et al., 2009; Ziberi et al., 2009; Bechara et al., 2010; Dugan et al., 2010; Menard and Ramsey, 2010; Wang et al., 2017; Vermeij et al., 2018