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. 2018 Jul 17;9:581. doi: 10.3389/fneur.2018.00581

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Copyright © 2018 Li, Weiland, Chen, Lan, Han, Durham, Liu, Wan, Ziai, Hanley and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transmission electron micrographs of striatum from sham mouse brain tissue. (A,B) The structure of the neuronal soma is visible with normal mitochondria (m), nucleus (n), and cytoplasm (c). The higher magnification image in (B) shows additional organelles, including Golgi body (g), lysosome (l), and ribosome (r). (C) Healthy, myelinated axons. Axons (a) are tightly wrapped by myelin, and axonal mitochondria (m) and neurofilaments are present. (D) A microglial cell is shown. Dark inclusions are indicated with red arrow heads. Scale bars: (A,D) 2 μm; (B,C) 500 nm. n = 6 animals per group.