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. 2018 Jul 17;9:581. doi: 10.3389/fneur.2018.00581

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Copyright © 2018 Li, Weiland, Chen, Lan, Han, Durham, Liu, Wan, Ziai, Hanley and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Degenerating axons at 3 days after intracerebral hemorrhage. (A,B) The axons show a severe loss of uniformity. Degenerating axons are indicated with red arrowheads. There is clear disruption of the myelin sheath and organelles, including autophagosomes (red arrows). (C,D) Dystrophic neurites (red arrows) are present in degenerating axons (red asterisks). A higher power image is shown in (D). Scale bars: (A,B,D) 500 nm; (C) 2 μm. r, red blood cell; m, mitochondria; a, axon. n = 6 animals per group.