FIGURE 4.
The effect of blestriacin on membrane potential and integrity of B. subtilis 168 (A) and S. aureus ATCC 29213 (B). Representative data from three independent cultures of both strains are shown following exposure to antimicrobial agents at 4× MIC for 2 h, except the incubation time of S. aureus ATCC 29213 with blestriacin was 3 h. Vancomycin was used as a negative control and nisin was used as a positive control. Con, no-drug treated control; Van, vancomycin (4 μg/mL); Nis, nisin (20 μg/mL). BP03, blestriacin.