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. 2018 Jul 17;5:89. doi: 10.3389/fcvm.2018.00089

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Copyright © 2018 Vilne and Schunkert.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kraus et al. (42) performed a pathway-level integrative analyses and observed associations of circulating short-chain dicarboxylacylcarnitine (SCDA) with variants in ER stress genes, whereof several genetic variants in FBXO25 and SUGT1 genes also demonstrated evidence of cis-regulation in expression quantitative trait loci (eQTL) analyses and independently predicted CAD events.