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. 2018 Jul 23;86(8):e00136-18. doi: 10.1128/IAI.00136-18

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Copyright © 2018 Lopez-Perez et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — Antibody responses to native PfEMP1 and recombinant PfEMP1 proteins produced in insect or CHO cells. IgG levels against recombinant (FV2_BIC and FV2_CHO) and the corresponding native (IT4VAR04) VAR2CSA-type PfEMP1 proteins were determined by an ELISA (recombinant proteins) or flow cytometry (native protein). (A) Individual FV2_CHO-specific IgG levels in all samples (sample sets 1 to 6). (B and C) Correlation (r_s) between IgG levels specific for FV2_BIC and FV2_CHO in Colombian (set 1 and set 2) (B) and Ghanaian (set 5) (C) samples. (D) Correlation (r_s) between IgG levels specific for FV2_CHO and the corresponding native VAR2CSA-type protein in Colombian samples (set 1 and set 2). The panel layout is the same as in Fig. 1.