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. 2018 Jul 23;86(8):e00136-18. doi: 10.1128/IAI.00136-18

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Copyright © 2018 Lopez-Perez et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 6 — Reactivity of PvDBP-specific IgG with recombinant PfEMP1 proteins. Shown are ELISA reactivities of PvDBP-specific human (DBL10) and mouse (3D10) monoclonal antibodies (mAb) (A, C, and E) and PvDBP-specific rabbit antiserum (B, D, and F) with the recombinant full-length PfEMP1 proteins FV2_BIC (A and B), FV2_CHO (C and D), and FV6_BIC (E and F). (A, C, and E) Reactivities of irrelevant (Ebola virus-specific) human monoclonal IgG (EBL040), mouse polyclonal IgG, as well as the VAR2CSA-type PfEMP1-specific human monoclonal antibody PAM1.4. (B, D, and F) IgG reactivities in human plasma pools from unexposed Colombians, infected pregnant Colombians, exposed Ghanaian women, unexposed Danish adults, and preimmune rabbit serum are shown for comparison. Serial 2-fold dilution series are shown for all antibody reagents.