Table 3. Outcomes for Patients With In-Hospital Cardiac Arrest Without vs With Intubation in the First 15 Minutes of Resuscitation in the Overall and Time-Dependent Propensity Score–Matched Cohorts.
Outcome | Unadjusted Analysis | Propensity Score–Matched Analysisa | ||||
---|---|---|---|---|---|---|
No. of Patients With Outcome/Total Patients (%) | Risk Ratio (95% CI) | No. of Patients With Outcome/Total Patients (%) | Risk Ratio (95% CI) | |||
No Intubation | Intubation | No Intubation | Intubation | |||
ROSC | 25 174/36 461 (69.0) | 42 366/71 611 (59.2) | 0.75 (0.73-0.76) | 25 685/43 310 (59.3) | 25 022/43 311 (57.8) | 0.97 (0.96-0.99) |
Survival to hospital discharge | 12 116/36 464 (33.2) | 12 140/71 615 (17.0) | 0.58 (0.57-0.59) | 8407/43 314 (19.4) | 7052/43 314 (16.3) | 0.84 (0.81-0.87) |
Favorable functional outcomeb | 8787/34 236 (25.7) | 7717/69 212 (11.2) | 0.55 (0.54-0.56) | 5672/41 733 (13.6) | 4439/41 868 (10.6) | 0.78 (0.75-0.81) |
Abbreviation: ROSC, return of spontaneous circulation.
Patients being intubated at any given minute (from 0-15 minutes; intubation group) were matched with patients at risk of being intubated within the same minute (ie, still receiving resuscitation; no intubation group) based on a time-dependent propensity score calculated from multiple patient, event, and hospital characteristics.
A cerebral performance category score of 1 (mild or no neurological deficit) or 2 (moderate cerebral disability) at hospital discharge was considered a good functional outcome.