Table 4.

Subgroup analyses for the outcome of event-free survival

Subgroups	No. of studies	HR (95% CI)	I2 (P value)
Population
Children	6	5.62 (3.75–8.42)	3.2% (0.40)
Mixed adult and children	2	3.60 (1.72–7.51)	65.2% (0.09)
Design
Prospective	5	5.33 (2.88–9.86)	57.6% (0.05)
Retrospective	3	4.59 (2.89–7.27)	0 (0.73)
Detection method
PCR	6	4.97 (2.93–8.44)	49.2% (0.08)
FC	2	4.77 (3.31–6.87)	0 (0.70)
Adjustment
Adjusted	4	4.56 (2.64–7.88)	48.9% (0.12)
Crude	4	5.18 (2.94–9.11)	24.4% (0.27)