Table 1.
<= 10 fractions | > 10 fractions | All patients | p-value | ||||
---|---|---|---|---|---|---|---|
n = 769 | n = 278 | n = 1047 | |||||
n | % | n | % | n | % | ||
Age (years) | |||||||
Mean (SD) | 63.3 +/− 10.7 | 62.5 +/− 12.0 | 63.1 +/− 11.1 | 0.330a | |||
Gender | |||||||
Male | 435 | 56.6 | 143 | 51.4 | 578 | 55.2 | 0.141b |
Female | 334 | 43.4 | 136 | 48.6 | 469 | 44.8 | |
Karnofsky-index | |||||||
Median (range) | 80 (40–100) | 80 (30–100) | 80 (30–100) | 0.696c | |||
Primary site | < 0.001b | ||||||
NSCLC | 356 | 46.3 | 69 | 24.8 | 425 | 40.6 | |
Breast cancer | 106 | 13.8 | 69 | 24.8 | 175 | 16.7 | |
Renal cancer | 88 | 11.4 | 71 | 25.5 | 159 | 15.2 | |
Other | 219 | 28.5 | 69 | 24.8 | 288 | 27.5 | |
Localization of metastases | 0.476b | ||||||
Cervical | 1 | 0.1 | 1 | 0.3 | 2 | 0.2 | |
Thoracic | 460 | 59.8 | 145 | 63.0 | 635 | 60.7 | |
Lumbar | 308 | 40.1 | 102 | 36.7 | 410 | 39.1 | |
Number of metastases | 0.329b | ||||||
Mean (SD) | 2.6 +/− 2.1 | 2.9 +/− 2.8 | 2.7 +/− 2.3 | 0.069a | |||
Solitary | 350 | 45.5 | 136 | 48.9 | 486 | 46.4 | |
Multiple | 419 | 54.5 | 142 | 51.1 | 561 | 53.6 | |
Other distant metastases | |||||||
Liver | 203 | 26.4 | 60 | 21.6 | 263 | 25.1 | 0.112b |
Brain | 112 | 14.6 | 30 | 10.8 | 142 | 13.6 | 0.119b |
Lung | 185 | 24.1 | 74 | 26.6 | 259 | 24.7 | 0.396b |
Tissue | 55 | 7.2 | 12 | 4.3 | 67 | 6.4 | 0.097b |
Antiresoptive treatment | 513 | 66.7 | 142 | 51.1 | 655 | 62.6 | < 0.001b |
Chemotherapy | 445 | 57.9 | 145 | 52.4 | 590 | 56.4 | 0.112b |
Stable metastases | 392 | 51.0 | 121 | 43.5 | 513 | 49.0 | 0.033b |
Unstable metastases | 377 | 49.0 | 157 | 56.5 | 534 | 51.0 | |
Orthopedic corset | 353 | 45.9 | 122 | 43.9 | 475 | 45.4 | 0.562b |
Radiotherapy schedule | |||||||
1 × 8 Gy | 1 | 0.1 | |||||
5 × 4 Gy | 11 | 1.0 | |||||
10 × 3 Gy | 757 | 72.3 | |||||
11 × 3 Gy | 1 | 0.1 | |||||
12 × 3 Gy | 1 | 0.1 | |||||
14 × 2.5 Gy | 92 | 8.8 | |||||
20 × 2 Gy | 184 | 17.6 |
Baseline characteristics of participants. Explanation: Others: colon cancer, neuroendocrine cancer, prostata cancer, ovarian cancer, urothelial cancer, uterine cancer, vulva cancer. Abbreviation: NSCLC non-small-cell lung carcinoma; at-test; bchi-square-test, cu-test