Table 2.

Tumor response to EGFR tyrosine kinase inhibitors

Response	Total (n=36)	EGFR mutation status of LA-MPEs
		EGFR MT (n=26)	EGFR WT (n=10)	p-value
Best overall response
PR	22 (61.1)	21 (80.8)	1 (10.0)	< 0.001
SD	5 (13.9)	1 (3.8)	4 (40.0)
PD	9 (25.0)	4 (15.4)	5 (50.0)

Values are presented as number (%). EGFR, epidermal growth factor receptor; LA-MPE, lung adenocarcinoma-associated malignant pleural effusion; MT, mutant type; WT, wild type; PR, partial response; SD, stable disease; PD, progressive disease.