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. 2017 Sep 18;50(3):894–907. doi: 10.4143/crt.2017.356

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Copyright © 2018 by the Korean Cancer Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — Expression of Snail in cancer associated fibroblasts of human colorectal cancer tissues and Kunming (KM) mice’s spontaneous colorectal cancers. (A, D) Masson staining of paraffin-embedded colorectal cancer tissue sections (×40) and the figure in the top right corner was enlarged (×400). (B, E) Activated fibroblast marker α-smooth muscle actin expression in paraffin-embedded colorectal cancer tissue sections was detected by immunohistochemistry. (C, F) Immunohistochemistry was used to detect the Snail expression. The paraffin-embedded colorectal cancer tissue sections of panels A, B and C were from human and panels D, E and F were KM mice’s spontaneous colorectal cancers tissue sections. Besides tumor cells, cancer-associated fibroblasts expressed Snail.