Table 1.
Patient and tumor characteristics
| Characteristic | No. (%) |
|---|---|
| Age at diagnosis, median (range, yr) | 47 (25-74) |
| FIGO stage | |
| IB | 202 (78.0) |
| IIA | 57 (22.0) |
| Histology | |
| Squamous cell carcinoma | 186 (71.8) |
| Adenocarcinoma | 48 (18.5) |
| Adenosquamous carcinoma | 11 (4.3) |
| Mucinous adenocarcinoma | 4 (1.5) |
| Small cell carcinoma | 3 (1.2) |
| Others | 7 (2.7) |
| Deep stromal invasion (%)a) | |
| ≤ 50 | 28 (11.4) |
| > 50 | 218 (88.6) |
| Bulky tumor (cm)a) | |
| ≤ 4 | 163 (66.8) |
| > 4 | 81 (33.2) |
| Lymphovascular invasiona) | |
| Negative | 51 (21.1) |
| Positive | 191 (78.9) |
| Parametrial extension | |
| Negative | 141 (54.4) |
| Positive | 118 (45.6) |
| Resection margin | |
| Negative | 222 (85.7) |
| Positive | 37 (14.3) |
| Pathologic N stage | |
| N0 | 52 (20.1) |
| N1 | 207 (79.9) |
| No. of harvested pelvic LNs | |
| Median (range) | 26 (4-85) |
| ≤ 25 | 125 (48.3) |
| > 25 | 134 (51.7) |
| No. of metastatic pelvic LNs | |
| Median (range) | 1 (0-19) |
| 0 | 52 (20.1) |
| 1 | 88 (34.0) |
| 2 | 44 (17.0) |
| ≥ 3 | 75 (29.0) |
| Para-aortic LN dissection | |
| Not done | 139 (53.7) |
| Done | 120 (46.3) |
| Para-aortic LN metastasis | |
| Absent | 110 (91.7) |
| Present | 10 (8.3) |
| Duration of radiotherapy (wk) | |
| ≤ 7 | 199 (76.8) |
| > 7 | 60 (23.2) |
| Consolidative chemotherapy | |
| Not done | 223 (86.1) |
| Done | 36 (13.9) |
| High-risk factor | |
| 1 | 168 (64.9) |
| 2 | 79 (30.5) |
| 3 | 12 (4.6) |
FIGO, International Federation of Gynecology and Obstetrics; LN, lymph node.
a)
Available cases analysis.