Table 3.

Factors associated preferences for patients' active participation and agreement between dyads

Characteristic	Patient responses			Caregiver responses			Agreement between dyads
	By hypothesized cognitive status			By hypothesized cognitive status			By hypothesized cognitive status
	Intact	Mild impairment	Severe impairment	Intact	Mild impairment	Severe impairment	Intact	Mild impairment	Severe impairment
Patient
Age, per year	0.94	0.96	0.96	-	-	-	1.02	1.01	1.03
	(0.91-0.97)	(0.92-0.99)	(0.91-1.01)				(0.97-1.07)	(0.96-1.06)	(0.96-1.11)
Female	0.66	0.63	0.72	-	-	-	0.87	1.03	1.66
	(0.41-1.05)	(0.39-1.02)	(0.33-1.57)				(0.5-1.53)	(0.58-1.82)	(0.71-3.91)
Higher education (≥ 12 yr)	1.25	1.82	3.05	-	-	-	1.82	0.67	0.44
	(0.75-2.09)	(1.11-2.99)	(1.53-6.09)				(1.02-3.26)	(0.40-1.15)	(0.22-0.86)
Caregiver
Age, per year	-	-	-	1.02	0.98	1.00	1.02	1.02	1.01
				(0.99-1.05)	(0.95-1.02)	(0.94-1.05)	(0.98-1.06)	(0.98-1.06)	(0.95-1.08)
Female	-	-	-	1.66	0.93	1.94	1.41	1.31	1.25
				(1.04-2.67)	(0.56-1.55)	(0.76-4.93)	(0.83-2.40)	(0.76-2.24)	(0.57-2.77)
Higher education (≥ 12 yr)	-	-	-	1.55	1.46	2.98	0.97	1.26	0.76
				(0.92-2.60)	(0.84-2.53)	(1.21-7.35)	(0.55-1.72)	(0.71-2.21)	(0.35-1.65)
Spouse	-	-	-	0.78	1.96	2.13	0.81	0.78	0.61
				(0.34-1.80)	(0.78-4.92)	(0.45-9.97)	(0.23-2.83)	(0.23-2.67)	(0.10-3.82)

Agreement between dyads was defined after dichotomization of the patients and caregiver responses into patients’ active participation (patient decision and patient dominance combined) vs. not (family dominance and family decision combined). Multivariate logistic regression analyses included patient variables (age, sex, and education) for patient responses, caregiver variables (age, sex, education, spouse vs. others) for caregiver responses, and both for agreement between dyads.