Table 6.
Virulence and antimicrobial resistance genes detected by microarray analysis exclusively among E. coli B2, D and F isolates from UTIs patients
| Type of infection | ||
|---|---|---|
| Hospital-acquired (n = 4) | Community-acquired (n = 14) | |
| Virulence genes (mean) | 39 | 32 |
| Antimicrobial resistance genes (mean) | 9 | 6 |
| Phylo-groups | B2 (n = 2) and D (n = 2) | B2 (n = 9), D (n = 3) and F (n = 2) |
| Virulence genes function | ||
| Resistance | blaTEM, blaOXA-1, blaPSE-1, blaCTX-M-15, blaCMY-2, mphA, ant(3″)-Ia (aadA1), aac(3)-IIa (aacC2), tet(A), tet(B), tet(30), tet(R), sulI sulII, qnrA, aac(6′)-Ib-cr, class 1 integron | blaTEM, blaOXA-1, blaOXA-9, blaPSE-1, blaCTX-M-15, blaCTX-M-12, blaOXY/K1, ant(3″)-Ia (aadA1), aac(3)-IIa (aacC2), aac(3)-IV, aph(3′)-Ia (aphA1), aph(3′)-IIa (aphA2), aph3 (strA), dhfrI, dhfrVII, catI, sulI, sulII, tet(A), tet(B), tet(30), mphA, class 1 integron, class 2 integron |
| Adhesins | afaD, afaD8, afaE1, afaE2, afaE5, bfpA, fimC, ibeB, csgA, csgE, f165(1)A, fimA, fimH, iha, lpfA(O113), papA(10), papA(11), papA(16), papA(8), papC, papGI2, fitA, sfaHII, sfaD | afaE1, afaE2, afaE5, cofA, lpfA2, fimC, csgA, csgE, csuA, F17b-A, F17d-A, facA, lpfA1, fimA, iha, lpfA(O113), lpfA, papA(8), papA(9), papA(10), papA(12), papA(13), papA(15), papA(40), papA(48), papC, papGII, papGIV, fitA, sfaHII, sfaA |
| Colcins and microsins | cvaC, mchB | cda, ce1a, cib, cvaC, mcbA. |
| Toxins | Sat | astA, astA(2), cdtB-4, cnf1, sat |
| Iron acquisition or transport system | chuA, fepC, fyuA, iroN, iroN(2), irp1, irp2, iucD, iutA, iutA(2), iutA(UPEC), sitA, sitD | chuA, fepC, fimH, fyuA, iroN(2), irp1, irp2, iucD, iutA, iutA(2), iutA(UPEC), sitA, sitD |
| Capsular and somatic antigens | kpsMTII, neuC | kpsMTII, neuA, neuC |
| Locus of enterocyte effacement (LEE) | eae(delta) | eae(lambda), espG, esta1 |
| ETT2 elements | eivG, eprJ | eivG, eprJ, epaS |
| Haemolysins and hemagglutinins | hlyA, hlyE, hra1 | bmaE, hlyA, hlyE, hra1. |
| Various functions | agn43, capU, ccdB, deoK, fliC, gad, iss, iss(3), malX, ompA, ompT, ompT(2), senB, traT | agn43, capU, ccdB, ibeA, ibeB, deoK, eaf, fliC, fliC(H7), gad, invX, iss, iss(3), malX, ompA, ompT, ompT(2), senB, traT |
| Newly recognized or putative E. coli virulence genes | artJ, b1121, b1432, gimB(orf1), mviM, mviN, shf, usp, virK | artJ, b1121, mviM, mviN, set, shf, usp, virK |