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. 2018 Jul 24;13:38. doi: 10.1186/s13024-018-0272-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Analysis of individual variants in the RA GRS on microglial density in the ventral medial caudate. Published effect sizes on the x-axis have been transformed using a natural logarithm and oriented in the positive direction to align allelic effects (color denotes direction of effect on microglial density). P-values (uncorrected) are two-sided and derived from robust iterated re-weighted least squares regression models, co-varying for age at death, sex, and three EIGENSTRAT principal components