Fig. 7.

OCM of CAA. (a) Schematic drawing of a cerebral artery with the arterial wall structure. White arrows indicate the most frequent positions where $\mathrm{A}\text{-}\beta$ accumulates. (b)–(c) Histological images (Congo red and hematoxylin staining). $\mathrm{A}\text{-}\beta$ accumulation in the arterial wall structure and $\mathrm{A}\text{-}\beta$ plaques can be seen. (d) En-face projection over the first $50\mu \mathrm{m}$ underneath the tissue surface. (e) Histological image (Congo red and hematoxylin staining) of a control cerebral artery, where no $\mathrm{A}\text{-}\beta$ accumulations can be found. (f) Attenuation B-scan image. (g) Corresponding intensity B-scan of (f). (h)–(i) Intensity B-scans acquired in CAA-affected brains. (j) OCM B-scan image of the control cerebral artery. Yellow arrows indicate the $\mathrm{A}\text{-}\beta$ accumulation in the arteries and red arrows $\mathrm{A}\text{-}\beta$ plaques in the surrounding tissue. Examples of manually segmented accumulations are included as well.