Table 2.

Patient characteristics of the trials included in the meta-analysis.

	Navarrete et al., 2011		Steinberg et al., 2014		Mohanty et al., 2015		Schneider et al., 2015
	PVI+CTI	CTI only	PVI+CTI	CTI only	PVI+TI	CTI only	PVI	CTI only
Subjects	23	25	25	25	108	108	20	23
Age, years	56±6	55±5	57.3±9.0	56.7±10.0	62.4±9.3	61.2±9.7	61.1±10	63.9±7.9
Male, %	NR	NR	76	52	73	75	75	91.3
Hypertension, %	69	52	88	76	52	46	85	91.3
Duration of AFL, months	4.4±1.2	4.5±1.1	30.5±23.6	27.0±17.8	34.2±7.6	33.1±5.8	NR	NR
LA diameter, cm	4.2±0.1	4.1±0.1	51.9±2.7	51.1±3.2	44.7±6	45.5±8	46.1±7.0	43.2±6.7
LVEF, %	53±3	55±3	56.0±3.4	55.1±4.3	57±11	59±10	53.7±13.6	55.5±11.5
AFL recurrence, %	NR	NR	0	0	0	0	15%*	8.7%
Freedom from arrhythmia, %	87	44	88	48	71.3	60.2	60**	39.1

AFL – atrial flutter; CTI – cavotricuspid isthmus; LA – left atrium; LVEF – left ventricular ejection fraction; PVI – pulmonary vein isolation; NR – not reported.

^*The data after single PVI procedure; the data were 5% after the second PVI procedure, and 0 after the third PVI procedure;

^**the data after the single PVI procedure; the data were 90% after mean 1.4 PVI procedures