Table 2.
Enriched pathways for the upregulated genes in PMNs phagocytizing iRBCs.
| Pathway | Count | p value | Genes |
|---|---|---|---|
| Mitogen-activated protein kinase (hsa04010) | 8 | 0.000442 | HCAR1, RPS6KA2, PEBP4, RIT2, MAPK8IP2, MLLT10, CDK5RAP1, HAS1 |
| Insulin receptor (hsa04910) | 4 | 0.000793 | LETM1, CISH, RIT2, SOCS3 |
| Jak-STAT signaling pathway (hsa04630) | 5 | 0.000731 | BATF2, CISH, SOCS3, MLLT10, CXCL10 |
| Interleukin signaling pathway (P00970) | 4 | 0.00139 | IL1A, IL15RA, NOS3, RPS6KA2 |
| Interferon-gamma signaling pathway (P00035) | 2 | 0.02225 | SOCS3, CISH |