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. 2018 Jul 6;9(52):29957–29974. doi: 10.18632/oncotarget.25722

Figure 8. Signaling pathways regulated by AQP1 in ESCC cells.

Figure 8

(A) Verification of gene expression by real-time quantitative RT-PCR. The expression levels of four selected Death receptor signaling pathway-related genes (FASL, BCL-2, XIAP, and FLIP) in AQP1- depleted TE5 and TE15 cells were compared to those in control siRNA-transfected cells using real-time quantitative RT-PCR. Mean ± SEM. n = 3. *p < 0.05 (significantly different from control siRNA). (B) The down-regulation of AQP1 increased the phosphorylation levels of JNK and the levels of Cleaved-caspase 3 in TE5 and TE15 cells.