Table 1. Correlation of microRNA-126 relative expression in tumor with clinicopathological characteristics of patient with cholangiocarcinoma.
Clinicopathological analysis in hilar cholangiocarcinoma | |||
---|---|---|---|
Variable | miR-126 low | miR-126 high | P |
No. of patients | 18 | 27 | |
Gender | 0.895 | ||
Female | 8 (44.4%) | 13 (46.4%) | |
Male | 10 (55.6%) | 14 (53.6%) | |
Patient age, years | 0.170 | ||
≤ 60 | 10 (55.6%) | 20 (75.0%) | |
> 60 | 8 (44.4%) | 7 (25.0%) | |
Tumor size | 0.0001 | ||
≤ 50 mm | 8 (44.4%) | 27 (100%) | |
> 50 mm | 10 (55.6%) | 0 (0%) | |
Pathologic N stage | 0.542 | ||
Positive | 7 (38.8%) | 14 (51.9%) | |
Negative | 11 (61.2%) | 13 (48.1%) | |
Histologic differentiation | 0.798 | ||
Well | 4 (22.2%) | 4 (14.8%) | |
Moderate/poor | 13 (77.8%) | 23 (85.2%) | |
Clinicopathological analysis in intrahepatic cholangiocarcinoma | |||
Variable | miR-126 low | miR-126 high | p |
No. of patients | 29 | 14 | |
Gender | 0.676 | ||
Female | 15 (55.6%) | 8 (57.1%) | |
Male | 14 (44.4%) | 6 (42.9%) | |
Patient age, years | 0.524 | ||
≤ 60 | 12 (41.4%) | 4 (28.6%) | |
> 60 | 17 (58.6%) | 10 (71.4%) | |
Tumor size | 0.967 | ||
≤ 50 mm | 9 (31.0%) | 4 (28.6%) | |
> 50 mm | 20 (69.0%) | 10 (71.4%) | |
Pathologic N stage | 0.013 | ||
Positive | 14 (47.4%) | 1 (7.1%) | |
Negative | 15 (52.6%) | 13 (92.9%) | |
Histologic differentiation | 0.529 | ||
Well | 20 (69.0%) | 9 (64.3%) | |
Moderate/poor | 9 (31.0%) | 5 (35.7%) |