Figure 4.

Results of YFV serology at 16-day post-infection. Neutralisation assays were performed on sera obtained from hamsters infected with re-encoded viruses that showed complete loss of mortality in vivo. For each virus, serum samples were retrieved at 16 dpi from two hamsters. Sera from both uninfected hamsters (n=2) and vaccinated humans (vaccinees, n=4) were used as negative and positive controls. Results are expressed as 50 per cent neutralisation titre (NT₅₀) and were evaluated using Graphpad Prism Software (v7.00 for Windows, GraphPad Software, La Jolla, CA, www.graphpad.com). Thick black lines indicate median values and minimum/maximum values are indicated by dashes.