Table 1.
Comparison of Baseline Clinical Characteristics in Patients With Respect to Adrenal Venous Sampling LI
| Characteristics | Total (N = 377) | LI 2–4 (n = 52) | LI 4–10 (n = 106) | LI > 10 (n = 219) | Overall P Value | Pairwise Comparison (P Values) |
||
|---|---|---|---|---|---|---|---|---|
| LI 2–4 vs LI 4–10 | LI 2–4 vs LI > 10 | LI 4–10 vs LI > 10 | ||||||
| Age, y | 52.0 ± 11.4 | 50.3 ± 10.2 | 52.6 ± 10.7 | 52.1 ± 12.0 | 0.47 | NA | NA | NA |
| Female, % | 46.9 | 53.8 | 34.9 | 51.1 | 0.01 | 0.079 | 1.0 | 0.019 |
| Body mass index | 24.4 ± 4.2 | 25.1 ± 3.7 | 25.0 ± 3.8 | 23.9 ± 4.4 | 0.028 | 1.00 | 0.19 | 0.06 |
| Systolic blood pressure, mm Hg | 141 ± 18 | 137 ± 18 | 142 ± 19 | 142 ± 18 | 0.22 | NA | NA | NA |
| Diastolic blood pressure, mm Hg | 86 ± 12 | 84 ± 12 | 88 ± 12 | 86 ± 12 | 0.078 | NA | NA | NA |
| Duration of hypertension, y | 10.6 ± 9.0 | 7.5 ± 7.1 | 10.9 ± 9.1 | 11.2 ± 9.2 | 0.031 | 0.092 | 0.027 | 1.0 |
| Defined daily dose of antihypertensive medications | 2.0 ± 1.3 | 1.7 ± 1.1 | 1.9 ± 1.1 | 2.1 ± 1.4 | 0.11 | NA | NA | NA |
| Diabetes mellitus, % | 16.4 | 13.4 | 22.1 | 14.4 | 0.22 | NA | NA | NA |
| Serum potassium, mEq/L | 3.3 ± 0.6 | 3.6 ± 0.5 | 3.5 ± 0.5 | 3.2 ± 0.5 | <0.01 | 0.49 | <0.01 | <0.01 |
| Estimated glomerular filtration rate, mL/min/1.73 m2 | 78 ± 22 | 87 ± 23 | 78 ± 20 | 77 ± 22 | <0.01 | 0.036 | <0.01 | 1.0 |
| Plasma aldosterone concentration, ng/dL | 35.7 ± 24.7 | 22.7 ± 15.6 | 25.8 ± 11.8 | 43.5 ± 27.8 | <0.01 | 1.0 | <0.01 | <0.01 |
| Plasma renin activity, ng/mL/h | 0.37 ± 0.42 | 0.42 ± 0.32 | 0.40 ± 0.30 | 0.34 ± 0.48 | 0.3 | NA | NA | NA |
| Ratio of plasma aldosterone concentration to plasma renin activity | 181 ± 224 | 85.1 ± 103 | 109 ± 117 | 239 ± 264 | <0.01 | 1.0 | <0.01 | <0.01 |
Data are presented as mean ± SD unless otherwise indicated.
Abbreviation: NA, not available.