Table 3.
Univariate and multivariate logistic regression for predictors of asthma medication and inappropriate asthma medication (xanthine derivatives) use, weighted to reflect the population of community dwelling U.S. adults 57–85 years of age. Univariate results reported as unadjusted odds ratios (ORs) and multivariate results reported as adjusted ORs (aORs) Analysis of inappropriate medications restricted to predictors of overall medication use (P<0.1). Some models had sample sizes <2976 due to missing data for certain variables. Bolded P-values significant (P<0.05).
| Asthma Medication (Univariate) (n = 2357–2976) |
Asthma Medication (Multivariate) (n = 2298, 8.4% med. usage) |
Inappropriate Asthma Medication (Univariate) (n = 2976) |
Inappropriate Asthma Medication (Multivariate) (n = 2976, 0.7% med. usage) |
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|---|---|---|---|---|---|---|---|---|
| Predictors | OR (95% CI) | P value | aOR (95% CI) | P value | OR (95% CI) | P value | aOR (95% CI) | P value |
| Age (decades) | 1.06 (0.90–1.24) | .47 | 1.03 (0.80–1.31) | .84 | ||||
| Male (vs. Female) | 0.84 (0.62–1.14) | .26 | 1.29 (0.89–1.88) | .18 | ||||
| Race/Ethnicity (vs. White) | .35 | .56 | ||||||
| Black | 0.64 (0.36–1.16) | 0.92 (0.42–2.03) | ||||||
| Hispanic | 1.15 (0.69–1.90) | 1.53 (0.74–3.19) | ||||||
| Other | 0.78 (0.30–1.99) | 1.11 (0.44–2.82) | ||||||
| Education (vs. <High school) | .22 | .79 | ||||||
| High school graduate or equivalent | .84 (0.61–1.16) | 1.17 (0.67–2.04) | ||||||
| Some college, vocational certificate, or associates | 1.06 (0.71–1.57) | 1.35 (0.62–2.96) | ||||||
| Bachelors or higher | 0.70 (0.47–1.04) | 0.99 (0.46–2.13) | ||||||
| Nasal surgery | 1.67 (1.00–2.79) | .049 | 1.16 (0.59–2.27) | .66 | ||||
| Asthma | 13.16 (9.72–17.82) | <.001 | 9.54 (5.48–16.62) | <.001 | 33.02 (8.70–125.23) | <.001 | 19.66 (3.18–121.70) | .002 |
| COPD | 28.36 (20.25–39.73) | <.001 | 24.21 (15.21–38.54) | <.001 | 13.11 (4.14–41.49) | <.001 | 4.25 (0.88–20.44) | .07 |
| Current alcohol use | 0.69 (0.52–0.92) | ..01 | 0.77 (0.49–1.21) | .26 | ||||
| Smoking (vs. Never) | <.001 | .51 | ||||||
| Former | 1.75 (1.29–2.36) | 1.30 (0.83–2.06) | ||||||
| Current | 1.84 (1.22–2.77) | 1.06 (0.45–2.47) | ||||||
| Insurance (vs. Private) | .14 | .45 | ||||||
| Medicare | 1.37 (0.97–1.94) | 1.29 (0.76–2.17) | ||||||
| Medicaid/VA/other | 1.01 (0.48–2.15) | 0.75 (0.23–2.46) | ||||||
| Comorbidity index | 1.13 (1.02–1.25) | .02 | 0.93 (0.83–1.05) | .24 | ||||