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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Mol Genet Metab. 2018 May 7;124(3):204–209. doi: 10.1016/j.ymgme.2018.05.001

Figure 4. Correlation between plasma amino acids and deoxysphingolipids in patients with PMDs.

Figure 4

a) Strong correlation between plasma serine/alanine ratio and DoxDHCer in PMD patients (light gray) vs controls (dark gray) (R2 = 0.74). b) No significant direct correlation between plasma serine/alanine ratio and DoxSO (R2 = 0.29), although there is clear clustering of PMD patients (light gray) versus controls (dark gray). DoxDhCer, deoxydihydroceramide; DoxSO, deoxysphingoids. The PMD data points differentiated by a circle around represent the patient with LHON plus (patient 6) who does not manifest peripheral neuropathy and who has an above average plasma serine level of 142 uM.