Table I.
Demographics of full cohort and stratifications by depression for N = 155,647 patients meeting the PAD algorithm from 2003-2014.
| Variable | All | Depression | No Depression | p-value |
|---|---|---|---|---|
| PAD patients in study, No. | 155,647 | 24,895 | 130,752 | |
| Age, Mean (SD), years | 66.7 (9.9) | 63.6 (9.4) | 67.3 (9.8) | <0.0001 |
| Sex, % Male | 98 | 96 | 98 | <0.0001 |
| Median Followup time (years) | 5.9 | 5.5 | 6.0 | <0.0001 |
| Race, % | 0.0234 | |||
| White | 83 | 83 | 83 | |
| Black | 16 | 16 | 16 | |
| Other | 1 | 1 | 1 | |
| Smoking, % | <0.0001 | |||
| Current | 45 | 50 | 44 | |
| Former | 41 | 37 | 42 | |
| Never | 14 | 13 | 14 | |
| BMI, Mean (SD), kg/m2 | 28.6 (6.2) | 29.1 (6.7) | 28.5 (6.1) | <0.0001 |
| Creatinine, Median (IQR), mg/dL | 1.1 (0.9-1.4) | 1.1 (0.9-1.3) | 1.1(0.9-1.4) | 0.0002 |
| Comorbidities, % | ||||
| Diabetes | 45.5 | 48.8 | 44.9 | <0.0001 |
| Hypertension | 84.2 | 85.0 | 84.1 | 0.0002 |
| CAD | 46.3 | 49.4 | 45.7 | <0.0001 |
| CHF | 16.4 | 19.3 | 15.9 | <0.0001 |
| COPD | 8.5 | 11.2 | 8.0 | <0.0001 |
| AF | 12.0 | 12.1 | 12.0 | 0.68 |
| Carotid Disease | 63.8 | 66.8 | 63.2 | <0.0001 |
| CKD or ESRD | 7.4 | 8.0 | 7.2 | <0.0001 |
| Statins, % | 72.1 | 73.7 | 71.7 | <0.0001 |
| Antiplatelets, % | 79.4 | 80.5 | 79.1 | <0.0001 |
| Antidiabetic medications, % | 39.7 | 43.0 | 39.1 | <0.0001 |
| Cilostazol, % | 8.0 | 7.0 | 8.2 | <0.0001 |
| Antidepressant (% taking any) | 36.2 | 84.7 | 26.9 | <0.0001 |
| Median Household Income of Residential Zip Code, % | 0.02 | |||
| <=$25,000 | 3.3 | 3.4 | 3.3 | |
| $25,001-$40,000 | 27.6 | 28.0 | 27.5 | |
| $40,001-$75,000 | 59.4 | 59.4 | 59.4 | |
| $75,001+ | 9.8 | 9.3 | 9.9 | |
| PAD severity, % | <0.0001 | |||
| Not Specified (per ICD-9 codes) | 68.5 | 68.0 | 68.6 | |
| Claudication | 20.2 | 19.5 | 20.3 | |
| Rest Pain | 3.9 | 4.0 | 3.9 | |
| Ulceration/Gangrene | 7.3 | 8.5 | 7.1 |
Abbreviations: SD, standard deviation; IQR, interquartile range; BMI, body mass index; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; CKD, chronic kidney disease; ESRD, end stage renal disease; mg, milligram; dL, deciliter.