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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2018 May 17;137:1–8. doi: 10.1016/j.prostaglandins.2018.05.009

Fig. 4. Ibuprofen affects sweat concentrations of nitric oxide synthase (NOS)-derived 9-nitrooleate and cytochrome P450 (CYP)-derived 20-hydroxyeicosatetraenoic acid (HETE).

Fig. 4

Oral administration of ibuprofen causes transient changes in sweat 9-nitrooleate and 20-HETE concentrations that appear to be inversely related. Data are presented as arithmetic mean ± standard deviation (n = 9), and temporal differences were evaluated using linear mixed models with Tukey’s post-hoc HSD. The false discovery rate (q) of the linear mixed models analysis was estimated according to the method of Storey and Tibshirani (2003).