Table 4.
SUVmax measurements in extracardiac sites of increased 18F-florbetaben uptake on delayed images
| Site of uptake | Patients | SUVmax (mean) | Patients with uptake (%) | Clinical/pathological organs involvement | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ||||
| Bone marrow | 3.2a,b | – | 2.4a | 3.2a,b | 3a | 3.4a | – | 3.4a,b | 4.7a | 3.3 | 7/9 (77%) | 4/9 (44%) |
| Spleen | 2.6a (D) | – | 1.1 (D) | – | 1.2 (D) | 1.1 (D) | – | 25.1a (D) | 16.7a (D) | 8 | 6/9 (66%) | |
| Kidneys | 1.6 | 1.8 | 1.3 | 1.9 | 2.1 | 1.9 | 1.9 | 6.4a | 5.9a | 2.8 | 9/9 (100%) | 5/9 (55%) |
| Stomach | 3.7a (D) | 3.9a (D) | 11.9a,b (F) | 4.9a (D) | 31.2a (D) | 5.9a (D) | – | – | – | 10.3 | 6/9 (66%) | 2/9 (22%) |
| Parotids | 1.2 (B) | 4 (B) | 3.4 (B) | 9.4a (B) | 4.5a (B) | 3.5 (B) | 1.1 (B) | 2.4 (B) | 5.3a (B) | 3.9 | 9/9 (100%) | |
| Submandibular Glands | – | – | – | – | – | – | – | 2.9 (B) | 4.4a (B) | 3.7 | 2/9 (22%) | |
| Lungs | – | 2.2a,b (F) | – | – | – | – | 2.7a (D) | – | – | 2.5 | 2/9 (22%) | 1/9 (11%) |
| Thyroid | – | 11.5a (B) | – | – | – | – | – | – | 5.8a (B) | 8.7 | 2/9 (22%) | |
| Orbital muscles | – | 4a,b (B) | – | – | 2.5a | – | – | – | – | 3.3 | 2/9 (22%) | |
| White matter | 2 | 1.8 | 2.9a | 2.5a | 2 | 2.8a | 0.8 | 2.8a | 3.4a | 2.3 | 9/9 (100%) | |
| Gray Matter | 1 | 0.9 | 3.4a | 2.9a | 1.3 | 1 | 0.8 | 2.6a | 1.6 | 1.7 | 9/9 (100%) | |
| Skeletal Muscles | – | 2.8a (B) | – | – | – | – | – | 2.2a | 4.5a (B) | 3.2 | 3/9 (33%) | |
| Tongue | – | 5.8a | 2.3 | – | 3.3a | – | – | – | 6.3a | 4.4 | 4/9 (44%) | 1/9 (11%) |
| Pleura | – | – | – | – | 5.7a (D) | – | 3.7a (D) | – | – | 4.7 | 2/9 (22%) | |
D diffuse, B bilateral, F focal
aIncreased uptake above adjacent background was considered abnormal
bPositive MRI:
• bone marrow (patients #1, 4, 8): non-specific heterogeneous T1w marrow signal
• lungs (patient #2): basilar lung consolidation with moderate right and mild left pleural effusions
• stomach (patient #3): area of asymmetric wall thickening and lack of enhancement
• ocular muscles (patient #2): mild predominantly lateral rectus muscle thickening