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FISH analysis. (A) Cosmid probe SNRPN; (B) D15S11; (C) GABRB3; (D) D15S10; (E) SNRPN subfragment F2 (Fig. 6A); (F) SNRPN subfragment F3 (Fig. 6A). In A–D, the labeled probes were purchased from Oncor, and a control locus PML cosmid probe was also included for identification of chromosome 15. It produces signals on 15q22. Arrows indicate der(15) (large arrow), der(19) (small arrow), or normal chromosome 15 (arrow head).
