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. 2018 Jul 24;8:11167. doi: 10.1038/s41598-018-29504-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

SAHA influences epigenetic gene expression. Quantitative RT-PCR results of HDAC1 and DNMT1 (a), EZH2 and MepC2 (b) in MRC5 treated with or without SAHA and/or TGF-β1. Data are expressed as Mean (±SD). One star (*) indicates a p ≤ 0.05, while two stars (**) indicate a p ≤ 0.01, compared to control group; ^# and ^##indicate a p ≤ 0.05 or p ≤ 0.01, respectively, compared to TGF-β1-treated group, two-tailed Student’s test.Three independent experiments were carried out with three replicatesfor each experimental condition.