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. 2018 Jul 1;175(16):3369–3378. doi: 10.1111/bph.14380

Figure 4.

Figure 4

Evaluation of the effects of the 5‐HT1A antagonist WAY 100635 on the actions exerted by the combination of CBD plus naltrexone (NTX) on ethanol self‐administration in C57BL/6J mice. (A) Number of active responses during the FR1 stabilization, FR1 + treatment and FR3 + treatment phases; (B) ethanol intake expressed as g·kg−1 of all groups during the FR1 stabilization, FR1 + treatment and FR3 + treatment; (C) breaking point achieved during PR. The dots and the columns represent the means and vertical lines ± the SEM. * Represents the values from CBD + NTX that are significantly different (P < 0.05) from VEH + VEH, WAY + VEH and CBD + NTX + WAY groups (n = 10 for each group).