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Actions of melatonin on chemo‐ and radiotherapy. Combination of melatonin with chemotherapeutic agents promotes survival, enhances the efficacy and immunomodulation and ameliorates toxicity due to chemotherapy, in patients with haematological neoplasms. Melatonin combined with radiotherapy promotes the apoptosis of haematological cancer cells while protecting the normal splenocytes, suggesting its selective cytotoxicity to haematological neoplasms.
