Table 1.
Summary of LD score regression
| SNP-based heritability | ||||
|---|---|---|---|---|
| Phenotype | Number of valid SNPs in analysis | h2SNP (95% CI) | Estimated intercept (se) | |
| 2016 IHGC migraine | 834,361 | 12.31% (9.17–15.45%) | 1.08 (0.015) | |
| 2013 PGC MDD | 877,768 | 19.10% (12.16–26.04%) | 1.01 (0.0083) | |
| SNP-based genetic correlation | ||||
|---|---|---|---|---|
| Phenotype 1 | Phenotype 2 | Number of valid SNPs in analysis | rG (se) [P value] | Estimated intercept for genetic covariance (se) |
| 2016 IHGC migraine | 2013 PGC MDD | 686,287 | 0.25 (0.12) [0.040] | 0.040 (0.0075) |
h2SNP SNP-based heritability, 95% CI 95% confidence interval, rG SNP-based genetic correlation, se standard error