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. 2018 Jul 24;9:2893. doi: 10.1038/s41467-018-05125-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — GluACTP expression disrupts experience-dependent structural plasticity in excitatory and inhibitory neurons. a Representative images of complete dendritic arbor reconstructions from time-lapse images taken before (T₁) and after (T₂) 4 h of dark, and after 4 h of STVE (T₃) of individual excitatory and inhibitory neurons in each group. Top: schematic shows the experimental protocol and imaging time course. b Summary data of changes in TDBL (ΔTDBL) and TBTN (ΔTBTN) during the dark and STVE periods in excitatory neurons. GluA1CTP and GluA2CTP significantly decrease STVE-induced dendritic arbor growth. *P < 0.05, **P < 0.01, Kruskal–Wallis test with post hoc Mann–Whitney U test. c Scatter plots of ΔTBTN in response to STVE versus dark in individual excitatory neurons. Rho value of Pearson correlation is shown on each plot. d Summary data of ΔTDBL and ΔTBTN during dark and STVE periods in inhibitory neurons. e Scatter plots of ΔTBTN in response to STVE versus dark in individual inhibitory neurons