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. 2018 Jul 24;9:2893. doi: 10.1038/s41467-018-05125-4

Fig. 4.

Fig. 4

GluACTP expression disrupts experience-dependent structural plasticity in excitatory and inhibitory neurons. a Representative images of complete dendritic arbor reconstructions from time-lapse images taken before (T1) and after (T2) 4 h of dark, and after 4 h of STVE (T3) of individual excitatory and inhibitory neurons in each group. Top: schematic shows the experimental protocol and imaging time course. b Summary data of changes in TDBL (ΔTDBL) and TBTN (ΔTBTN) during the dark and STVE periods in excitatory neurons. GluA1CTP and GluA2CTP significantly decrease STVE-induced dendritic arbor growth. *P< 0.05, **P< 0.01, Kruskal–Wallis test with post hoc Mann–Whitney U test. c Scatter plots of ΔTBTN in response to STVE versus dark in individual excitatory neurons. Rho value of Pearson correlation is shown on each plot. d Summary data of ΔTDBL and ΔTBTN during dark and STVE periods in inhibitory neurons. e Scatter plots of ΔTBTN in response to STVE versus dark in individual inhibitory neurons