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. 2018 Jul 18;9:1673. doi: 10.3389/fimmu.2018.01673

Figure 2.

Figure 2

OX40 and α4β7 expression during the homeostatic proliferation (HP) process of human naïve CD4 T-cells. Untouched CFSE-stained naïve CD4 T-cells were culture in presence of rIL7 (10 ng/ml) and with irradiated autologous APCs (1/1 ratio): (A) representative CFSE histograms used for identification of different types of HP at baseline (0 day) and after 10 days of culture, (B) OX40, α4-integrin, and β7-integrin upregulation during HP, (C) frequencies of OX40 in the different types of HP subsets, (D) frequencies of α4+β7+ in the different types of HP subsets, (E) frequencies of α4highβ7high in the different types of HP subsets. Frequencies of both OX40 and α4β7 were calculated after background substation from baseline condition. Data are expressed as mean value and SD.