Figure 6.

Schematic diagram for main functions of tetraspanins and their partners in B cells. Dotted lines enclose coreceptors formed by tetraspanins and partners. Lines between tetraspanins and partners or coreceptors indicate the interactions which have functions in B cells (line with arrow) in seven biologic processes, such as cell activation, antigen presentation, and antibody production. One tetraspanin or partner can have one or more functions on B cells. Same colored lines with arrows point to similar function or regulation.