Table 6.
MIC (µg/mL) values in the presence of [CoCl2(dap)2]Cl (1) and [CoCl2(en)2]Cl (2) passaging results for selected strains of Candida spp.
| Strains | Compound | Initial MIC (µg/mL) | MIC after 20 passages (µg/mL) |
|---|---|---|---|
| C. albicans ATCC 10231 | [CoCl2(dap)2]Cl (1) | 62.5 ± 4.04 | 250 ± 19.79 |
| [CoCl2(en)2]Cl (2) | 62.5 ± 8.47 | 250 ± 16.16 | |
| C. albicans 12823 | [CoCl2(dap)2]Cl (1) | 62.5 ± 4.95 | 250 ± 16.16 |
| [CoCl2(en)2]Cl (2) | 62.5 ± 4.04 | 250 ± 32.31 | |
| C. glabrata ATCC 2001 | [CoCl2(dap)2]Cl (1) | 16 ± 1.97 | 125 ± 8.08 |
| [CoCl2(en)2]Cl (2) | 16 ± 1.06 | 125 ± 9.89 | |
| C. glabrata 11644 | [CoCl2(dap)2]Cl (1) | 16 ± 1.06 | 125 ± 9.89 |
| [CoCl2(en)2]Cl (2) | 16 ± 2.41 | 125 ± 8.08 | |
Data shown are mean ± SD.